America’s #1 Comedy Club Guide
America’s #1 Comedy Club Guide
South Carolina’s comedy culture is a growing blend of Southern charm, storytelling tradition, and modern wit. Rooted in the region’s love for tall tales and eccentric characters, local comedians often draw from their own experiences with Southern life, politics, and social quirks. Cities like Charleston, Columbia, and Greenville have become comedy hubs, offering stand-up nights, improv shows, and open mic events in small clubs, theaters, and breweries.
The culture values personable humor—often self-deprecating or observational—with a regional twist that highlights the idiosyncrasies of Southern living. While the state is more conservative than others, its comedy scene balances edge with respect, often relying on cleverness over crudeness.
Touring acts frequently stop in for performances, but it’s the homegrown talent that’s slowly gaining recognition. Whether through grassroots festivals or social media sketches, South Carolina’s comedy scene is carving out a unique voice that’s as warm and sharp as its hospitality.
Charleston, SC’s improv and sketch comedy scene is alive with warmth, creativity, and strong traditions. At its heart is Theatre 99, a downtown hub that runs shows almost every weekends—Wednesday, Friday, Saturday nights—featuring long‑form improv, audience‑suggestion shows, and sketch‑improv hybrids that keep things fresh.
Locally born troupes like The Have Nots! give consistency and character to the scene, performing regularly and mentoring new talent. Events run the gamut: there are family‑friendly clean shows, edgier late‑night performances, and improv parties where the audience plays a role, offering suggestions that shape every moment.
Every year, the Charleston Comedy Festival showcases both local and visiting sketch and improv acts, broadening the scene’s reach and challenging performers with new styles. Venues are eclectic—black boxes, small theaters, hidden alleys—making performances feel personal and experimental.
The vibe in Charleston is community‑oriented: laughter shared among neighbors, emerging artists supported, and comedy seen not just as entertainment, but as something collaborative and alive.
Wit’s End Comedy Lounge is a lively and intimate venue where laughter takes center stage. Known for its welcoming atmosphere and diverse lineup, the lounge offers a rotating schedule of stand-up, improv, and themed comedy nights that cater to all tastes.
From seasoned headliners to emerging local talent, every show delivers fresh, high-energy performances in a space designed for connection and fun. Comfortable seating, great acoustics, and a full-service bar make it an ideal spot for date nights, group outings, or spontaneous nights out.
The venue frequently hosts open mic events, giving aspiring comedians a chance to shine in front of an engaged crowd. With a commitment to fostering a supportive comedy community, Wit’s End creates an experience that feels both professional and personal. Whether you’re a longtime comedy fan or just looking for a night of laughter, Wit’s End Comedy Lounge delivers entertainment with heart and humor.
Address: 3320 Rivers Ave, North Charleston, SC 29405
Phone: (843) 261-1136
Website: Wit’s End Comedy Lounge
Hours: Contact the club to confirm.
Greenville, SC has developed a lively improv and sketch comedy scene, built around institutions, troupes, workshops, and regular performance nights. Alchemy Comedy Theater is a central fixture: since 2011 it has put on improv, sketch, and hybrid comedy shows nearly every Thursday through Saturday.
These shows often combine local performers with visiting artists, and incorporate varied formats—everything from improv game‑style performances to sketch, to more experimental pieces. The theater also offers structured class tracks for improv, starting with basic scene work and progressing into long‑form narratives and pattern play.
For those just dipping their toes in, there are monthly improv jams and drop‑in shows where students and seasoned performers both participate. The New South Comedy Festival, hosted in Greenville, brings together sketch, improv, and stand‑up from across the region, injecting fresh voices and broader exposure.
Greenville’s improv and sketch landscape balances polished weekly shows with raw creative energy, fostering both community growth and experimentation.
The Comedy Zone Greenville is a premier comedy club offering top-notch entertainment in the heart of downtown Greenville, South Carolina. Known for its vibrant atmosphere and intimate setting, the club hosts a rotating lineup of nationally touring comedians, rising stars, and local talent.
With shows scheduled weekly, guests can enjoy a fresh mix of stand-up acts that cater to a variety of comedic tastes. The venue features comfortable seating, excellent acoustics, and a full-service bar offering drinks and light bites.
Whether you’re planning a fun night out with friends, a unique date experience, or just looking to laugh, The Comedy Zone delivers a high-energy, memorable evening. Special events and themed nights add to the excitement, and tickets are affordably priced for easy access to great live comedy. The Comedy Zone Greenville continues to be a staple in the city’s entertainment scene, where laughter is always center stage.
Address: 221 N Main St, Greenville, SC 29601
Phone: (864) 603-1583
Website: The Comedy Zone Greenville
Hours: Contact the club to confirm.
Myrtle Beach, SC boasts a fun and varied comedy scene rooted in improv, sketch, magic, and audience‑engagement shows—perfect for locals and vacationers alike. One of the main hubs is Carolina Improv, which stages regular improv sketches and long‑form shows in the Uptown Theater. Their performances often draw on local flavor—tourism, beach culture, and quirky day‑to‑day scenes—to create relatable, spontaneous laughs.
Alongside that, the Comedy Cabana serves as a longstanding home for stand‑up comedy, featuring both touring comedians and emerging local voices, often in an intimate club atmosphere with food and drink. Shows typically run multiple nights per week, especially during peak seasons. Myrtle Beach also leans into variety entertainment: comedy‑magic shows, hypnosis evenings, and interactive performances help diversify the comedic offerings. The scene balances polish with casual fun; you might plan an evening out around a polished stand‑up set or just drop in for a light, improvisational performance with some audience participation. It’s lively, accessible, and never too formal.
Comedy Cabana is Myrtle Beach’s longest-running comedy club, delivering laughs for over two decades. This iconic venue is known for its lively atmosphere, professional production, and consistently hilarious shows featuring top-tier comedic talent.
Each week, the club welcomes nationally recognized headliners along with emerging stand-up stars, offering a diverse range of humor that appeals to all tastes. The intimate setting ensures every seat has a great view of the stage, creating an engaging and personal experience for every guest.
With a full-service bar and food menu, Comedy Cabana is the perfect spot for a night out, whether you’re a local or visiting the Grand Strand. The club’s laid-back vibe, friendly staff, and commitment to quality entertainment make it a standout destination for comedy lovers. From date nights to group outings, Comedy Cabana delivers nonstop laughs and unforgettable memories in one of South Carolina’s most popular coastal cities.
Address: 9588 N Kings Hwy, Myrtle Beach, SC 29572
Phone: (843) 449-4242
Website: Comedy Cabana
Hours: Contact club to confirm.
South Carolina’s improv and sketch comedy scene has been steadily blossoming, with hubs in cities like Greenville, Charleston, and Columbia providing both depth and experimental spirit. Greenville’s Alchemy Comedy Theater emerges as a standout, balancing polished sketch‑revues with long‑form improv, weekly shows, and education programs that nurture writers and performers.
Columbia supports its own community flavor through groups like The Mothers, staging monthly improv and sketch performances that blend regional humor and artistic voice. In Charleston, Theatre 99 leads with regular improv shows that invite audience participation, showcasing both quick‑fire comic games and more developed scene work.
Beyond performances, there’s strong emphasis on training: classes, writing labs, and workshops are vital parts of the scene, helping sketch teams refine material and improvisors build confidence. Across the state, festivals like the New South Comedy Festival bring outside talent in, mix styles, and push local artists to new heights. The scene’s strength comes not just from big nights, but from the daily routine of open mics, small stages, and performers taking risks.
